Nuclear energy is a carbon-free, large-scale, and stable power source and an important baseload power source from the viewpoint of energy security. Therefore, we recognize that continuous usage of nuclear energy is essential in order to achieve carbon neutrality in Japan by 2050. Mitsubishi Heavy Industries, Ltd. (MHI) is supporting electric utilities for the restart of existing plants in Japan and the early completion of the construction of specialized safety facilities, along with supporting the early establishment of the nuclear fuel cycle. Furthermore, MHI is developing an advanced light water reactor "SRZ-1200" that will ensure the world's highest level of safety, and also developing various other types of reactors to meet a diverse set of societal needs in the future. This report describes efforts within our nuclear energy business and associated efforts to ensure achievement of carbon neutrality by 2050.